Zolium 0.25

Zolium 0.250.25mg

Type:10 Tablets

Generic Name:Alprazolam

Manufacturer:Incepta Pharmaceuticals Ltd.

Price:20.00

Ad

Indication

Oral Short-term management of anxiety Adult: 0.25-0.5 mg tid, increased to 3-4 mg daily if necessary. Elderly: Initially, 0.25 mg bid/tid. Panic attacks Adult Immediate-release 0.5 mg PO q8hr; may increase q3-4Days by ?1 mg/day Average dose: 5-6 mg/day PO May require up to 10 mg/day PO divided q8hr Extended-release 0.5-1 mg PO qDay; may increase q3-4Days by <1 mg/day Average dose: 3-6 mg PO qDay Anxiety Associated With Depression 1-4 mg/day PO divided q8hr Hepatic impairment: Avoid in severe impairment.

Administration

Potentiates action of alcohol and CNS depressants. Reduced conc with cigarette smoking by 50%. Potentially Fatal: Cimetidine and fluoxetine reduce the clearance of alprazolam. Alprazolam enhances activity of imipramine and desipramine.

Adult Dose

Dosage reduction or gradual withdrawal. Dependence. Geriatric or debilitated patients. Muscle weakness, impaired hepatic or renal function; arteriosclerosis; obesity; depression particularly suicidal tendency; chronic pulmonary insufficiency. May impair ability to drive or operate machinery. Children <18 yr. Lactation: Enters breast milk/not recommended

Renal Dose

Alprazolam has anxiolytic, muscle-relaxant, anticonvulsant, antidepressant and sleep-modifying effects. It binds to the ? aminobutyric acid (GABA)-specific sites throughout the CNS, leading to an increase in the inhibitory effect of GABA on neuronal excitability. Increased neuronal permeability to chloride ions thus results in hyperpolarisation and stabilisation.

Contraindication

<18 years old: Not recommended

Mode of Action

Administration May be taken with or without food. Side effects eg sleepiness/drowsiness may be reduced if taken immediately after meals.

Precaution

Anxiety disorders, Panic disorders, Nausea due to chemotherapy

Side Effect

Renal impairment: Use caution; not studied

Pregnancy Category Note

>10% (4 mg dose) Drowsiness (41%),Depression (10-15%),Headache (10-15%),Constipation (10-15%),Diarrhea (10-15%),Dry mouth (10-15%) >10% (10 mg dose) Drowsiness (77%),Impaired coordination (40-50%),Increased appetite (30-35%),Fatigue (30-35%),Memory impairment (30-35%),Irritability (30-35%),Decreased salivation (30-35%),Cognitive disorders (20-30%),Insomnia (20-30%),Dcreased appetite (20-30%),Headache (20-30%),Lightheadedness (20-30%),Dysarthria (20-30%),Diarrhea, constipation, and nausea/vomiting (20-30%),Weight change (20-30%),Nasal congestion (15-20%),Decreased or increased libido (10-15%),Menstrual disorder (10-15%),Difficult micturition (10-15%) 1-10% (4 mg dose) Tachycardia (5-10%),Confusion (5-10%),Insomnia (5-10%),Nausea/vomiting (5-10%),Blurred vision (5-10%),Nasal congestion (5-10%),Hypotension (1-5%),Syncope (1-5%),Akathisia (1-5%),Dizziness (1-5%),Increased salivation (1-5%),Nervousness (1-5%),Tremor (1-5%),Weight change (1-5%) 1-10% (10 mg dose) Increased salivation (5-10%),Talkativeness (1-5%),Incontinence (1-5%) Potentially Fatal: Blood dyscrasias.

Interaction

Acute narrow-angle glaucoma, preexisting CNS depression or coma, resp depression, acute pulmonary insufficiency or sleep apnoea; severe hepatic impairment; pregnancy, lactation.

Alternative brand of Zolium 0.25

AlprocontinAlprocontin

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳0.00

Mundipharma (Bangladesh) Pvt. Ltd.

Xanax 0.25Xanax 0.25

  • 0.25mg
  • Tablet
  • Alprazolam

Price: ৳10.00

Navana Pharmaceuticals Ltd.

Alprax XR 1Alprax XR 1

  • 1mg
  • Tablet
  • Alprazolam

Price: ৳40.00

Opsonin Pharma Limited

Zolax 0.5Zolax 0.5

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳20.00

Beximco Pharmaceuticals Ltd.

Alprax 0.25Alprax 0.25

  • 0.25mg
  • Tablet
  • Alprazolam

Price: ৳15.00

Opsonin Pharma Limited

Xanax 0.5Xanax 0.5

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳25.00

Navana Pharmaceuticals Ltd.

Alzolam 0.25Alzolam 0.25

  • 0.25mg
  • Tablet
  • Alprazolam

Price: ৳15.00

Sun Pharmaceutical (Bangladesh) Ltd.

SerelamSerelam

  • 0.25mg
  • Tablet
  • Alprazolam

Price: ৳1.00

General Pharmaceuticals Ltd.

Zolium 0.5Zolium 0.5

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳34.00

Incepta Pharmaceuticals Ltd.

Alprax XR 2Alprax XR 2

  • 2mg
  • Tablet
  • Alprazolam

Price: ৳80.30

Opsonin Pharma Limited

XioticXiotic

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳2.00

Globe Pharmaceuticals Ltd.

Zolium XR 1Zolium XR 1

  • 1mg
  • Tablet
  • Alprazolam

Price: ৳40.00

Incepta Pharmaceuticals Ltd.

Zolium XR 2Zolium XR 2

  • 2mg
  • Tablet
  • Alprazolam

Price: ৳80.00

Incepta Pharmaceuticals Ltd.

SerelamSerelam

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳2.01

General Pharmaceuticals Ltd.

Xolam XRXolam XR

  • 1mg
  • Tablet
  • Alprazolam

Price: ৳4.00

Aristopharma Limited

Xolam XRXolam XR

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳2.50

Aristopharma Limited

Alprax 0.5Alprax 0.5

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳30.00

Opsonin Pharma Limited

AlaxenAlaxen

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳0.00

United Chemicals & Pharmaceuticals Ltd.

Alzolam 0.5Alzolam 0.5

  • 0.5mg
  • Tablet
  • Alprazolam

Price: ৳30.00

Sun Pharmaceutical (Bangladesh) Ltd.

Alzolam SR 1Alzolam SR 1

  • 1mg
  • Tablet
  • Alprazolam

Price: ৳4.02

Sun Pharmaceutical (Bangladesh) Ltd.