Type:15gm tube
Generic Name:Miconazole 2% Oral Gel
Manufacturer:Beximco Pharmaceuticals Ltd.
Price:৳52.00
Oropharyngeal candidiasis, Oral thrush, Denture stomatitis, Fungal infections of the mouth, Throat and gut, Angular cheilitis, Dermatomycoses, Tinea pedis, Tinea corporis, Tinea cruris, Tinea versicolor
Apply on oral lesions and retain in the mouth as long as possible before swallowing. For localised lesions of the mouth, a small amount of gel may be applied directly to the affected area with a clean finger.
Mouth/Throat Oropharyngeal candidiasis, Intestinal candidiasis Adult: The usual dose is 15 mg/kg/day in divided doses. One or two tea spoonfuls (5-10 ml) of gel four times daily. Continue treatment for at least 1 wk after symptoms have disappeared. Localised lesions of mouth: Smear small amount on affected area with clean finger 4 times daily for 5-7 days.
Mouth/Throat Oropharyngeal candidiasis Children aged 6 years and over: One tea-spoonful (5 ml) of gel four times daily. Children aged 2-6 years: One tea-spoonful (5 ml) of gel twice daily. Infants under 2 years: Half tea-spoonful (2.5 ml) of gel twice daily. Continue treatment for at least 1 wk after symptoms have disappeared. Localised lesions of mouth: Smear small amount on affected area with clean finger 4 times daily for 5-7 days.
Miconazole Oral Gel is contraindicated in patients with known hypersensitivity to any of its components and in patients with liver dysfunction.
Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.
Caution is required particularly in infants & young children to ensure that the gel does not obstruct the throat. Lactation: Unknown whether distributed in breast milk, caution advised
1-10% Diarrhea (6%),Nausea (4.6%),Headache (5%),Dysgeusia (2.9%),Upper abdominal pain (2.5%),Vomiting (2.5%)
May increase anticoagulant effect of warfarin. May increase or prolong the effect of the following drugs: Oral hypoglycaemics (e.g. sulfonylureas), phenytoin, HIV protease inhibitors (e.g. saquinavir), antineoplastic agents (e.g. vinca alkaloids, busulfan, docetaxel), Ca channel blockers (e.g. dihydropyridines, verapamil), immunosuppressive agents (e.g. ciclosporin, tacrolimus, sirolimus), carbamazepine, cilostazol, buspirone, disopyramide, alfentanil, sildenafil, alprazolam, brotizolam, midazolam IV, rifabutin, methylprednisolone, trimetrexate, ebastine and reboxetine. Potentially Fatal: Increased risk of cardiac arrhythmia w/ astemizole, cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine, sertindole, terfenadine. May increase exposure to ergot alkaloids leading to ergotism. May increase the risk of rhabdomyolysis w/ HMG-CoA reductase inhibitors (e.g. simvastatin and lovastatin). May increase the effect of triazolam and oral midazolam.
