Rafex

Rafex30mg/5ml

Type:50ml bot

Generic Name:Fexofenadine Hydrochloride

Manufacturer:Team Pharmaceuticals Ltd.

Price:48.00

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Indication

Allergic rhinitis, Hay fever, Urticaria, Allergy

Administration

Should be taken on an empty stomach. Take before meals. Do not take w/ fruit juice.

Adult Dose

Adults: Allergic rhinitis: 120 mg once daily or 60 mg twice daily Urticaria: 180 mg once daily

Child Dose

Children: Tablet 2-12 years: 30 mg (1 spoonful) or 5 ml twice daily 6 months-2 years: 15 mg (1/2 spoonful) or 2.5 ml twice daily >12 years: 60 mg PO BID OR 180 mg PO qDay ODT 6-12 years: 30 mg PO BID

Renal Dose

Adult: Initially, 60 mg once daily. Child: 6 mth-<2 yr: 15 mg once daily and 2-11 yr: 30 mg once daily. >12 years: 60 mg PO qDay, initially

Contraindication

Hypersensitivity.

Mode of Action

Fexofenadine, an active metabolite of terfenadine, is a competitive peripheral histamine H1-receptor antagonist on effector cells in the GI tract, blood vessels and respiratory tract.

Precaution

Renal impairment. Pregnancy, lactation; children <6 yr. Lactation: Excretion in milk unknown; use with caution (AAP states “compatible with nursing”)

Side Effect

>10% Vomiting (6-12%) 1-10% Headache (5-10%),Cough (4%),Diarrhea (3-4%),URTI (3%),Back pain (2-3%),Pyrexia (2%),Dysmenorrhea (2%),Dizziness (2%),Stomach discomfort (2%),Pain in extremity (2%),Somnolence (1-3%),Rhinorrhea (1-2%)

Pregnancy Category Note

Pregnancy category: C Lactation: Excretion in milk unknown; use with caution (AAP states “compatible with nursing”)

Interaction

Co-admin with ketoconazole or erythromycin may increase plasma levels of fexofenadine. May increase adverse effects of other anticholinergics and CNS depressants. May increase arrhythmogenic effect of antipsychotic agents (phenothiazines); avoid concurrent usage. May reduce the efficacy of betahistine. Pramlintide may increase the anticholinergic effect of fexofenadine. Bioavailability may be increased by verapamil. Efficacy may be reduced by rifampin.

Alternative brand of Rafex

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Albion Laboratories Ltd.

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