Xerova EZ 10/10

Xerova EZ 10/1010mg+10mg

Type:7 Tablets

Generic Name:Atorvastatin + Ezetimibe

Manufacturer:Beacon Pharmaceuticals Ltd.

Price:112.00

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Indication

Hypercholesterolaemia, Primary Hyperlipidemia

Administration

May be taken with or without food.

Adult Dose

Oral Hypercholesterolaemia Adult: Per tablet contains atorvastatin 10 mg and ezetimibe 10 mg: Usual starting: 1 tablet once daily.

Child Dose

Safety and efficacy not established

Contraindication

Hypersensitivity; active liver disease or unexplained persistent elevated liver function tests. Pregnancy and lactation.

Mode of Action

Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonate which is an early rate-limiting step in cholesterol biosynthesis. Ezetimibe inhibits the absorption of cholesterol from the intestine, thus decreasing the delivery of intestinal cholesterol to the liver.

Precaution

Hepatic impairment; patients consuming substantial quantities of alcohol with a history of liver disease. Not recommended for use in children <10 yr. Lactation: Because of the potential for adverse reactions in nursing infants, women taking this drug should not breast feed. Contraindicated in breastfeeding women.

Side Effect

1-10% Increased ALT (5%),Increased AST (4%),Musculoskeletal pain (4%),Abdominal pain (3%),Nausea (3%),Arthralgias (3%),Muscle weakness (2%),Dizziness (2%),Hyperkalemia (2%),Hot flushes (2%),Coughing (2%),Bronchitis (2%),Sinusitis (2%)

Pregnancy Category Note

Pregnancy Category: X Lactation: Because of the potential for adverse reactions in nursing infants, women taking this drug should not breast feed. Contraindicated in breastfeeding women.

Interaction

Atorvastatin: Increases digoxin levels; increases anticoagulant effect of warfarin. Avoid the combination of HMG-CoA reductase inhibitors and fibrates. Ezetimibe: Cholestyramine decreases AUC of ezetimibe by approx 55%; ciclosporin may increase ezetimibe levels. Potentially Fatal: Antacids decrease atorvastatin levels; colestipol decreases atorvastatin plasma levels; propranolol decreases antihyperlipidaemic activity of atorvastatin.

Alternative brand of Xerova EZ 10/10

Liptor EZ 10/10Liptor EZ 10/10

  • 10mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳160.00

The ACME Laboratories Ltd.

Ezitor 10/10Ezitor 10/10

  • 10mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳140.00

Navana Pharmaceuticals Ltd.

Taven EZ 20/10Taven EZ 20/10

  • 20mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳220.00

Renata Limited

Xerova EZ 20/10Xerova EZ 20/10

  • 20mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳168.00

Beacon Pharmaceuticals Ltd.

Ezitor 20/10Ezitor 20/10

  • 20mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳220.00

Navana Pharmaceuticals Ltd.

Taven EZ 10/10Taven EZ 10/10

  • 10mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳140.00

Renata Limited

Atova EZ 10/10Atova EZ 10/10

  • 10mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳210.00

Beximco Pharmaceuticals Ltd.

Anzitor EZ 10/10Anzitor EZ 10/10

  • 10mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳140.00

Square Pharmaceuticals PLC.

Atova EZ 20/10Atova EZ 20/10

  • 20mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳330.00

Beximco Pharmaceuticals Ltd.

Anzitor EZ 20/10Anzitor EZ 20/10

  • 20mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳220.00

Square Pharmaceuticals PLC.

Liptor EZ 20/10Liptor EZ 20/10

  • 20mg+10mg
  • Tablet
  • Atorvastatin + Ezetimibe

Price: ৳240.00

The ACME Laboratories Ltd.