Medicase - Aclene Plus Gel - 10gm tube - 0.1% + 2.5% - Adapalene 0.1% + Benzoyl Peroxide 2.5%

Aclene Plus Gel0.1% + 2.5%

Type:10gm tube

Generic Name:Adapalene 0.1% + Benzoyl Peroxide 2.5%

Manufacturer:Drug International Ltd.

Price:৳150.00

Indication

Apply a thin film of adapalene and benzoyle peroxide gel to affected areas of the face and/or trunk once daily after washing. Use a pea-sized amount for each area of the face (e.g., forehead, chin, each cheek). Avoid the eyes, lips and mucous membranes.

Administration

Adapalene: Increased irritation may occur with medicated or abrasive soaps, products with a pronounced drying effect and those containing alcohol or astringents. Benzoyl Peroxide: PABA sunscreens may transiently discolour fabric.

Adult Dose

Exposure to sunlight, including sunlamps, should be minimized during the use of adapalene and benzoyle peroxide gel. Patients with high levels of sun exposure and those with inherent sensitivity to sun should exercise particular caution. Use of sunscreen products and protective apparel, (e.g., hat) are recommended when exposure cannot be avoided. Weather extremes, such as wind or cold, may be irritating to patients under treatment with adapalene and benzoyle peroxide gel. Safety and effectiveness of Adapalene and Benzoyl peroxide gel in pediatric patients under the age of 9 years have not been established.

Renal Dose

Adapalene binds to specific retinoic acid nuclear receptors which normalises the differentiation of follicular epithelial cells resulting in decreased microcomedone formation. Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its oxidative property. It is active against S.epidermidis and P.acne.

Contraindication

Child: >9 years: Apply thin film to affected facial areas and/or trunk qPM after washing <9 years: Safety & efficacy has not been established.

Precaution

Acne

Pregnancy Category Note

>10% Stinging/ burning (3-41%),Dryness (1-41%),Scaling (1-35%),Erythema (1-27%) 1-10% Contact dermatitis (3%),Application site burning (2%),Application site irritation (1%),Skin irritation (1%)