Mupiron

Mupiron2%

Type:10gm tube

Generic Name:Mubirocin 2% Topical

Manufacturer:Eskayef Pharmaceuticals Ltd.

Price:140.00

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Indication

Impetigo, Folliculitis, Secondary skin infections

Adult Dose

Topical/Cutaneous Impetigo Adult: As 2% oint: Apply to affected area tid for 5-10 days; re-evaluate after 3-5 days if no clinical response. Secondary skin infections Adult: As 2% cream: Apply to affected area tid for up to 10 days; re-evaluate after 3-5 days if no clinical response.

Child Dose

Topical/Cutaneous Impetigo Child: >2 mth Apply to affected area tid for 5-10 days; re-evaluate after 3-5 days if no clinical response. Secondary skin infections Child: >3 mth Apply to affected area tid for up to 10 days; re-evaluate after 3-5 days if no clinical response.

Contraindication

This drug is contraindicated in individuals with a history of sensitivity reactions to Mupirocin or any of the components of the preparation.

Mode of Action

Mupirocin inhibits protein synthesis of the bacteria by binding to isoleucyl transfer RNA-synthetase. It is active against gram-positive and some gram-negative bacteria.

Precaution

Patient w/ extensive burns and wounds. Renal impairment. Childn. Pregnancy and lactation. Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi Lactation: Not known if distributed into milk; recommended that nursing be temporarily discontinued during therapy

Side Effect

Burning, stinging, pruritus, pain, rash, erythema, dry skin, tenderness, cellulitis, pain or bleeding secondary to eczema, secondary wound infection, urticaria, swelling, increased exudates, contact dermatitis, furunculosis, exfoliative dermatitis. Rarely, systemic reactions (e.g. nausea, headache, dizziness, abdominal pain, ulcerative stomatitis, systemic allergic reactions).

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