Zymarin Ophthalmic Solution

Zymarin Ophthalmic Solution0.50%

Type:5ml drop

Generic Name:Gatifloxacin Eye prep

Manufacturer:Eskayef Pharmaceuticals Ltd.

Price:125.00

Ad

Indication

Bacterial conjunctivitis

Adult Dose

Ophthalmic Bacterial conjunctivitis Adult: As 0.3% soln: Instill 1 drop 2 hrly into affected eye(s) while awake (up to 8 times daily) for the 1st 2 days then reduce to 1 drop 4 times daily while awake for the next 5 days.

Child Dose

Ophthalmic Bacterial conjunctivitis Child: >1 yr: As 0.3% soln: Instill 1 drop 2 hrly into affected eye(s) while awake (up to 8 times daily) for the 1st 2 days then reduce to 1 drop 4 times daily while awake for the next 5 days.

Contraindication

Patients with a history of hypersensitivity to Gatifloxacin, to other quinolones, or to any of the components in this medication. Eye drops should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye.

Mode of Action

Gatifloxacin is a fluoroquinolone antibacterial which acts by inhibiting DNA synthesis in susceptible organisms via inhibition of both DNA gyrase (essential for bacterial reproduction) and topoisomerase IV (essential during bacterial cell division).

Precaution

Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis. Avoid contaminating the applicator tip with material from the eye, fingers or other source.

Side Effect

1-10% Conjunctival irritation (5-10%),Incr. lacrimation (5-10%),Keratitis (5-10%),Papillary conjunctivitis (5-10%),Conjunctival hemorrhage (1-4%),Chemosis (1-4%),Dry eye (1-4%),Eye discharge (1-4%),Eye irritation (1-4%),Eye pain (1-4%),Eyelid swelling (1-4%),Red eye (1-4%),Visual acuity decr (1-4%),Taste disturbance (1-4%)

Interaction

Additive effect w/ drugs that prolong QT interval e.g. antiarrhythmic agents (amiodarone, quinidine, sotalol), arsenic trioxide, cisapride, chlorpromazine, droperidol, mefloquine, dolasetron, mesoridazine, moxifloxacin, pimozide, tacrolimus, pentamidine, thioridazine, ziprasidone. Increased risk of blood glucose disturbances w/ drugs that alter blood glucose concentrations (e.g. antidiabetics). Systemic admin may elevate plasma concentrations of theophylline, interfere caffeine metabolism, enhance effects of oral anticoagulant (warfarin and its derivatives), and transient elevations in serum creatinine w/ ciclosporin.

Alternative brand of Zymarin Ophthalmic Solution

Gatiflox Eye DropsGatiflox Eye Drops

  • 0.30%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳100.00

Incepta Pharmaceuticals Ltd.

Lotenol GLotenol G

  • 0.5%+0.3%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳290.00

Popular Pharmaceuticals Ltd.

Tget 0.3%Tget 0.3%

  • 0.30%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳100.00

Opsonin Pharma Limited

TagTag

  • 0.30%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳100.00

Aristopharma Limited

GatigenGatigen

  • 0.30%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳100.30

General Pharmaceuticals Ltd.

GatiproGatipro

  • 0.50%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳130.00

Incepta Pharmaceuticals Ltd.

GatiproGatipro

  • 0.30%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳100.00

OSL Pharma Limited,

GatibacGatibac

  • 0.30%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳100.00

Popular Pharmaceuticals Ltd.

Gatiflox ESGatiflox ES

  • 0.50%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳125.00

Incepta Pharmaceuticals Ltd.

ZymarZymar

  • 0.30%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳208.00

GatsinaGatsina

  • 0.30%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳100.00

The Ibn Sina Pharmaceutical Ind. Ltd.

XegalXegal

  • 0.30%
  • Eye Drops
  • Gatifloxacin Eye prep

Price: ৳90.00

Beximco Pharmaceuticals Ltd.