Oryza

Oryza0.15%w/v

Type:250ml bot

Generic Name:Benzydamine Mouth prep

Manufacturer:Incepta Pharmaceuticals Ltd.

Price:225.00

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Indication

Pain or irritation of the mouth and throat, Acute Pharyngitis, Radiation-Associated Mucositis

Administration

Rinse the 15 ml mouthwash around the mouth or use it as a gargle. After 20 to 30 second, spit it out. Do not swallow the mouthwash.

Adult Dose

Mouth/Throat Pain or irritation of the mouth and throat, Acute pharyngitis Adult: Rinse or gargle 15 ml of a 0.15% solution (diluted with water if stinging occurs) every 1½ to 3 hours until remission of pain.. Radiation-Associated Mucositis Gargle or rinse 15 mL in mouth (for 30 seconds, followed by expulsion from mouth) 3-4 times per day Begin treatment 1 day prior to radiation therapy and continue daily during treatment

Contraindication

Benzydamine Hydrochloride is contraindicated in subjects with a history of hypersensitivity to any of its components.

Mode of Action

Benzydamine Hydrochloride predominantly acts by inhibiting the synthesis of pro inflammatory cytokines like tumour necrosis factor-alpha (TNF-α) and interleukin-1β (IL-1β) without largely affecting other pro inflammatory cytokines. Moreover, it is capable of a local anaesthetic effect that may be related to its capability for inhibiting the release of inflammatory mediators like substance P.

Precaution

The use of undiluted benzydamine Hydrochloride may produce local irritation manifested by burning sensation in patients with mucosal defects. If necessary, it may be diluted (1:1) with lukewarm water. Since it is absorbed from the oral mucosa and excreted mostly unchanged in the urine, a possibility of its systemic action has to be considered in patients with renal impairment.

Side Effect

1-10% Burning /stinging sensation,Nausea/vomiting,Numbness Frequency Not Defined Cough,Drowsiness,Dry mouth,Headache,Pharyngeal irritation

Pregnancy Category Note

Pregnancy Category: Not available. Safety has not been established in pregnant women. Lactation: excretion in milk unknown; use with caution

Alternative brand of Oryza

Benostar MouthwashBenostar Mouthwash

  • 0.15%w/v
  • Mouthwash
  • Benzydamine Mouth prep

Price: ৳150.00

Square Pharmaceuticals PLC.

OryzaOryza

  • 0.15%w/v
  • Mouthwash
  • Benzydamine Mouth prep

Price: ৳120.00

Incepta Pharmaceuticals Ltd.