Konakion

Konakion2mg/0.2ml

Type:1 amps

Generic Name:Phytomenadione (Vitamin K1)

Manufacturer:Roche Bangladesh Pharmaceutical

Price:98.00

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Indication

Vitamin K deficiency, Over-anticoagulation, Vitamin K deficiency bleeding

Administration

May be taken with or without food.

Adult Dose

Oral Vitamin K deficiency due to drugs or malabsorption Adult: 10-40 mg daily. Over-anticoagulation Adult: Up to 5 mg may be used. Dose depends on INR and degree of haemorrhage. Intravenous Over-anticoagulation Adult: 0.5-5 mg via slow IV inj. Dose depends on INR and degree of haemorrhage.

Child Dose

Intramuscular Prophylaxis of vitamin K deficiency bleeding in neonates Child: Neonate: 0.5-1 mg, given as a single dose via IM inj. Alternatively, 2 mg may be given orally, followed by a 2nd dose of 2 mg after 4-7 days. Parenteral Vitamin K deficiency bleeding in neonates Child: Infant: 1 mg by IV/IM/SC inj, further doses may be given if necessary

Contraindication

Hypersensitivity.

Mode of Action

Phytomenadione promotes hepatic synthesis of clotting factors. It is a naturally occurring compound that is used to prevent and treat haemorrhages related to vitamin K deficiency.

Precaution

Increased risk of severe haemolytic anaemia in neonates after large doses; severe hepatic impairment; pregnancy. Premature neonates weighing <2.5 kg. Lactation: Excreted in breast milk; use caution

Side Effect

Anaphylaxis, dyspnoea, cyanosis, pain, swelling, phloebitis at the Inj site, diaphoresis, dizziness, hypotension (rare), allergic reactions after SC and IM inj.

Interaction

Decreased effect of oral anticoagulants.

Alternative brand of Konakion

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