Medicase - Pepcon Plus - 200ml bot - 480mg+20mg/5ml

Pepcon Plus480mg+20mg/5ml

Type:200ml bot

Generic Name:Magaldrate + Simethicone

Manufacturer:Leon Pharmaceuticals Ltd.

Price:৳110.33

Indication

Heartburn, Hyperacidity, Indigestion, Dyspepsia, Gastritis, Peptic ulcers, GERD

Administration

Take between meals & at bedtime.

Adult Dose

Oral Adult: Suspension: 2-4 teaspoonful orally 3-4 times daily after 20-60 minutes of meals and at bedtime.

Child Dose

Children 12 years and older: Suspension: 2-4 teaspoonful orally 3-4 times daily after 20-60 minutes of meals and at bedtime.

Contraindication

Magaldrate is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal functions.

Mode of Action

Magaldrate is a hydroxymagnesium aluminate complex that is rapidly converted in gastric acid to magnesium and aluminium hydroxide, which is poorly absorbed and provides a sustained antacid effect with balanced efects on intestinal motility; increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying. Simethicone allows gas bubbles in the stomach and intestines to come together more easily, which allows for easier passage of gas.

Precaution

Care should be taken in decreased kidney function, hypophosphataemia and weak people.

Side Effect

Chalky taste, Constipation, Fecal impaction, Stomach cramps, Nausea,Vomiting. Loose stool.

Interaction

Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.