Type:Injection
Generic Name:Somatostatin
Manufacturer:
Price:৳4405.00
GI haemorrhage
Intravenous Gastrointestinal haemorrhage Adult: Initially, 250 mcg as a bolus inj over 3-5 min, followed by a continuous infusion of 3.5 mcg/kg/hr until bleeding has ceased. May continue for a further 48-72 hr to prevent recurrent bleeding.
Somatostatin is a polypetide obtained synthetically or from the hypothalamus. It acts by inhibiting the release of growth hormone from the anterior pituitary. It also inhibits the release of thyrotrophin and corticotropin from the pituitary, glucagon and insulin from the pancreas. It also regulates duodenal and gastric secretions. It may also play a role in pain perception.
Monitor blood glucose levels. May inhibit intestinal absorption thus concomitant parenteral nutrition may be recommended.
Rapid infusion may lead to abdominal discomfort, nausea, flushing, bradycardia.
Lengthens the time of hexobarbital-induced sleep & potentiates the action of pentetrazol.