Bepogen

Bepogen1.50%

Type:5ml drop

Generic Name:Bepotastine Besilate 1.5% Eye prep

Manufacturer:General Pharmaceuticals Ltd.

Price:320.00

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Indication

Allergic conjunctivitis

Adult Dose

Instill one drop into the affected eye(s) twice a day.

Child Dose

<2 years old: Safety & efficacy not established >2 years old: Administer as in adults;Instill one drop into the affected eye(s) twice a day.

Contraindication

Hypersensitivity.

Mode of Action

Bepotastine is direct H1-receptor antagonist and an inhibitor of the release of histamine from mast cells.

Precaution

To minimize the risk of contamination, do not touch dropper tip to any surface. It should not be used to treat contact lens-related irritation. Patients should be advised not to wear contact lens when using this drop. Lactation: excretion in milk unknown; use with caution

Side Effect

>10% Mild taste disturbance 1-10% Ocular irritation,Headache,Nasopharyngitis

Pregnancy Category Note

Pregnancy There are no available human data for use during pregnancy to inform any drug-associated risks; oral administration of bepotastine besilate to pregnant rats or rabbits during organogenesis or during pre/postnatal period did not produce adverse embryofetal or offspring effects at clinically relevant systemic exposures; maternal toxicity was observed in rabbits at lowest dose administered, 20 mg/kg/day (215 times the maximum recommended human ophthalmic dose, RHOD, on a mg/m² basis) Lactation There are no data on human milk, effects on breastfed infant or milk production; developmental and health benefits of breastfeeding should be considered, along with mother’s clinical need for therapy, and any potential adverse effects on breastfed infant

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