Permethi

Permethi5%

Type:30gm tube

Generic Name:Permethrin 5% Topical

Manufacturer:Pharmasia Ltd.

Price:50.00

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Indication

Scabies, Pediculosis pubis

Adult Dose

Topical Scabies Adult: (30 gm tube) : A full tube. Apply to skin surfaces from neck to toes. Wash off after 8-14 hr. May reapply in 7 days Pediculosis capitis, Pediculosis pubis Apply to washed hair and leave on for 10 mins before rinsing with water. May reapply in 7 days

Child Dose

Topical Scabies Children over 12 years(30 gm tube) : A full tube. Children aged 6-12 years : Up to 1/2 of a tube. Children aged 1-5 years : Up to 1/4 of a tube. Children aged 2 months to 1 year: Up to 1/8 of a tube. Apply to skin surfaces from neck to toes. Wash off after 8-14 hr. May reapply in 7 days Pediculosis capitis, Pediculosis pubis Apply to washed hair and leave on for 10 mins before rinsing with water. May reapply in 7 days

Contraindication

Hypersensitivity.

Mode of Action

Permethrin is a pyrethroid pediculocide and scabicide. It causes paralysis and death of the pest by inhibiting sodium ion influx through nerve cell membrane channels delaying repolarisation.

Precaution

Avoid contact with eyes and mucous membranes. Cross-sensitivity may occur with ragweed or chrysanthemums. History of asthma. Pregnancy and lactation. Lactation: Not known if distributed in breast milk; may temporarily withhold the drug while the mother is nursing

Side Effect

1-10% Mild and transient burning and stinging (10%) Pruritus (7%)

Interaction

Mild and transient burning, stinging, pruritus, erythema, tingling, numbness, rash; difficulty in breathing; phototoxic or photosensitisation reactions.

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