Type:10 Tablets
Generic Name:Terbutaline Sulphate
Manufacturer:The Ibn Sina Pharmaceutical Ind. Ltd.
Price:৳10.00
Acute bronchospasm
May be taken with or without food.
Oral Acute bronchospasm Adult: Initiate at 2.5 mg three/four times daily Maintenance: 5 mg three times daily q6hr while patient is awake; reduce dose to 2.5 mg q6hr Not to exceed 15 mg/Day
Oral Acute bronchospasm Child: <12 years: 0.05 mg/kg three times daily initially; increase PRN, not to exceed 5 mg/day 12-15 years: 2.5 mg PO q6hr 3 times daily; not to exceed 7.5 mg/day >15 years: 5 mg/dose PO q8hr three times daily; reduce dose to 2.5 mg q6hr; not to exceed 15 mg/24hr
Renal Impairment GFR <50 mL/min: reduce dose by 50% GFR >50mL/min: Dose adjustment not necessary
Hypersensitivity to sympathomimetics. Any condition of mother or foetus in which prolongation of pregnancy is dangerous.
Terbutaline is a direct-acting sympathomimetic which relaxes bronchial smooth muscle by selective action on beta2 receptors. It also decreases uterine contractility.
Patient w/ thyrotoxicosis, HTN, DM, ketoacidosis, CV disorders (e.g. ischaemic heart disease), convulsive disorders, coronary insufficiency or associated arrhythmias. Childn. Pregnancy and lactation. Monitoring Parameters Monitor cardiorespiratory function, serum K and glucose levels; Lactation: Distributed into breast milk, but in amounts generally considered insufficient to affect nursing infants (AAP Committee states compatible with nursing)
Tachycardia, nervousness, tremor, palpitations, dizziness, headache, nausea, vomiting, anxiety, restlessness, lethargy, drowsiness, weakness, flushes, sweating, chest discomfort, muscle cramps, tinnitus. Rarely, seizures, hypersensitivity vasculitis, elevated liver enzymes. Potentially Fatal: Increased heart rate, transient hyperglycaemia, hypokalaemia, cardiac arrhythmias, pulmonary oedema, myocardial ischaemia.
Antagonised effects of beta-blockers. Increased risk of hypokaelemia with xanthine derivatives, corticosteriods and diuretics; increased risk of arrhythmias with inhaled anaesthetics, sympathomimetics.
