Seravent HFA

Seravent HFA25mcg

Type:200 Puffs

Generic Name:Salmeterol

Manufacturer:Drug International Ltd.

Price:200.00

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Indication

Chronic asthma, COPD

Adult Dose

Inhalation Asthma Prevention and Maintenance, COPD Maintenance Adult: As inhaler: 2 puffs (50 mcg) twice daily; up to 100 mcg twice daily if needed. Prevention of Exercise-Induced Asthma 2 puffs (50 mcg) at least 30 min prior to exercise.

Child Dose

Inhalation Child > 4 years Asthma Prevention and Maintenance, COPD Maintenance As inhaler: 2 puffs (50 mcg) twice daily; up to 100 mcg twice daily if needed. Prevention of Exercise-Induced Asthma 2 puffs (50 mcg) at least 30 min prior to exercise.

Contraindication

Contraindicated in patients with hypersensitivity to Salmeterol or to the any excipient of this preparation. Monotherapy in the treatment of asthma. Treatment of status asthmaticus, other acute episodes of asthma or COPD.

Mode of Action

Salmeterol is a direct-acting sympathomimetic which relaxes bronchial smooth muscle by its selective action on beta 2 receptors with little effect on heart rate.

Precaution

Patient w/ CV disease, CNS disorders, DM, hyperthyroidism, hypokalaemia, seizure disorders, ketoacidosis. Not intended for the relief of acute bronchospasm. Hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor pulmonary function, BP, heart rate, CNS stimulation, hepatic function; glucose and K levels..

Side Effect

>10% Headache (13-17%),Pain (1-12%) 1-10% Nasal congestion (9%),Hypertension (4%),Edema (1-3%),Dizziness (4%),Sleep disturbance (1-3%),Migraine (1-3%),Contact dermatitis (1-3%),Urticaria (3%),Hyperglycemia (1-3%),Articular rheumatism (1-3%),Paresthesia (1-3%),Muscular stiffness (1-3%),Photodermatitis (1-2%),Bronchitis (7%),Influenza (5%),Rigidity (1-3%),Rhinitis (5%),Asthma (3%) Frequency Not Defined Conjunctivitis,Hyperglycemia,Keratitis,Oral candidiasis,Chest tightness,Cataracts,Hypokalemia,Myositis

Interaction

Diuretics, corticosteroids and xanthines may augment hypokalaemia. Risk of severe hypertension when used with MAOIs, TCAs and other sympathomimetics. Increased susceptibility to cardiac arrhythmias caused by digoxin and other cardiac glycosides.

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