Type:Tablet
Generic Name:Flutamide
Manufacturer:Beacon Pharmaceuticals Ltd.
Price:৳0.00
Prostate cancer
May be taken with or without food.
Oral Palliative treatment of prostatic carcinoma Adult: 250 mg tid preferably at least 3 days before gonadorelin analogue treatment.
Hypersensitivity, severe hepatic impairment, pregnancy and lactation.
Flutamide is a nonsteroidal 'pure' antiandrogen which acts directly on the target tissues either by blocking androgen uptake or by inhibiting cytoplasmic and nuclear binding of androgen.
Perform liver function tests before starting treatment and at regular intervals. Treatment is not recommended in patients whose ALT values exceed twice the upper limit of normal. Regular assessment of prostate specific antigen level may help to monitor disease progression. Advise patient against discontinuing drug on their own. Exercise caution in patients with cardiac disease. Lactation: Excretion in milk unknown; not recommended
>10% Hot flashes (61%),Decreased libido (36%),Impotence (31%),Diarrhea (12%),Nausea/vomiting (11%) 1-10% Gynecomastia (9%),Anorexia (4%),Edema (4%),Leukopenia (3%),Rash (3%) Frequency Not Defined Hemolytic anemia, methemoglobinemia Increased AST, ALT, bilirubin, BUN
Pregnancy Category: D Lactation: Excretion in milk unknown; not recommended
Increased prothrombin time in patients on long-term warfarin treatment.
