Type:Tablet
Generic Name:Griseofulvin
Manufacturer:GlaxoSmithKline
Price:৳5.88
Dermatophytosis
Should be taken with food. Take immediately after meals.
Oral Dermatophytosis Adult: 0.5-1 g daily in single or divided doses. Treatment duration: 2-8 wk (hair and skin infections); up to 6 mth (fingernail infections); >12 mth (toenail infections).
Oral Dermatophytosis Child: PO 20–25 mg/kg q24h
Severe liver disease; porphyria; monilial infection; SLE; pregnancy.
Griseofulvin is a fungistatic antibiotic that inhibits fungal cell division at metaphase and binds to human keratin making it resistant to fungal infections. It has activity against common dermatophytes including epidermophyton, Microsporum, or Trichophyton spp.
Lactation; may impair ability to drive or operate machinery; avoid exposure to intense sunlight or artificial light. Regular monitoring of the renal, hepatic and blood tests should be done. Lactation: Excretion in milk unknown; avoid use because of potential tumorigenicity
Oral thrush; GI distress, taste perversion; dizziness, confusion, headache, depression, insomnia, fatigue; peripheral neuritis, photosensitivity; skin rashes, urticaria, erythema multiforme; leucopenia, proteinuria. Potentially Fatal: Hepatotoxicity; angioedema.
Antagonises oral anticoagulants and oral contraceptives. Decreased GI absorption with phenobarbital. Reduced plasma concentrations with enzyme inducers e.g. phenylbutazone and hypnotics. Potentially Fatal: Enhances effects of alcohol and causes disulfiram-like reaction.