Erdostin

Erdostin300mg

Type:8 Capsules

Generic Name:Erdosteine

Manufacturer:NIPRO JMI Pharma Limited

Price:120.00

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Indication

Symptomatic treatment of acute exacerbations of, chronic bronchitis, in adults as an expectorant.

Administration

The capsules must be swallowed whole with a glass of water.

Adult Dose

Oral As a mucolytic Adult: 300 mg bid. Max duration: 10 days. Hepatic Failure Since there are no data in patients with severe liver failure, the use of erdosteine is not recommended in these patients. Mild to Moderate Hepatic Failure Dose should be reduced

Renal Dose

Since there are no data in patients with creatinine clearance <25ml/min, the use of erdosteine is not recommended in these patients.

Contraindication

Hypersensitivity to the active substance or to any of the other excipients. Active peptic ulcer.

Mode of Action

Erdosteine contains two sulfhydryl groups, which are freed after metabolic transformation in the liver. The liberated sulfhydryl groups break the disulphide bonds, which hold the glycoprotein fibres of mucus together. This makes the bronchial secretions more fluid and enhances elimination.

Precaution

Pregnancy, lactation.

Side Effect

Epigastralgia, nausea, vomiting, loose stools, spasmodic colitis, headache.

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