Artesunet

Artesunet50mg

Type:Tablet

Generic Name:Artesunate

Manufacturer:Gaco Pharmaceuticals(G.A Company Ltd)

Price:12.00

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Indication

Falciparum malaria especially in quinidine-resistant patients Adult: PO: 4 mg/kg once daily x3 days (with mefloquine)

Administration

Antimalarial potentiating action seen with mefloquine, primaquine and tetracycline. Additive effect with chloroquine. Antagonistic effect with pyrimethamine and sulphonamides.

Adult Dose

Hepatic or renal insufficiency. Pregnancy and lactation. Lactation: unknown

Renal Dose

Artesunate is a potent and rapidly-acting blood schizontocide derived from the leaves of the chinese herb, Armesia annua. The exact mode of action is not clear but clinical studies have confirmed the effectiveness of artesunate in P. vivax and falciparum malaria. Unclear, may inhibit DNA replication & transcription.

Precaution

Malaria, Schistosomiasis

Pregnancy Category Note

Generally well-tolerated, Cardiotoxicity (high doses), Neurotoxicity observed in animal studies, Drug induced fever, Skin rash

Interaction

Hypersensitivity.

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